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Most patients who use oral corticosteroids can occasionally tolerate a relatively rapid taper after a response is achieved; a prolonged steroid taper is rarely necessary to prevent relapse.
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John GR, Stark WJ "Periorbital urticarial drug reaction associated with intravenously administered methylprednisolone.
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Criteria for withholding or delaying antibiotic therapy for acute otitis media (AOM) include (1) patient older than 2 years, (2) normal host, (3) intact tympanic membrane, (4) at least 3-6 months since last episode of otitis media (OM), (5) receptive parents, and (6) assurance of medical follow-up care.
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Note that the level of the inflammatory marker calprotectin in feces correlates significantly with colonic inflammation in both ulcerative colitis and Crohn disease.
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Following the intravenous injection of methylprednisolone sodium succinate, demonstrable effects are evident within one hour and persist for a variable period.
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According to the Faculty of Sexual and Reproductive Healthcare Clinical Effectiveness Unit in the United Kingdom, women with IBD should plan for conception when their disease is stable and well controlled.
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There may be decreased resistance and inability to localize infection when corticosteroids are used.
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