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The researchers reported that 66 percent of patients completed at least eight cycles of therapy with all three drugs, and 55 percent of patients continued into the maintenance phase of the trial.

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Of these cases, 47 resulted in hospitalization and 9 in pneumonia.

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Our findings regarding the use of carfilzomib in combination with lenalidomide and dexamethasone reinforce and extend the evidence in support of using a three-drug regimen composed of a proteasome inhibitor, an immunomodulatory agent, and dexamethasone in patients with relapsed multiple myeloma.

If you are on this medication for a long period of time, you may be more susceptible to infection.

Explanations of all diagnostic tests and their findings, as well as the treatment plan, are important.

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Muscle wasting, muscle pain or weakness, delayed wound healing, and atrophy of the protein matrix of the bone resulting in osteoporosis, vertebral compression fractures, aseptic necrosis of femoral or humeral heads, or pathologic fractures of long bones are manifestations of protein catabolism that may occur during prolonged therapy with glucocorticoids.

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Four highly sensitive tests are recommended by the Endocrine Society for the screening of Cushing syndrome: 24-hour urinary free cortisol, late-night salivary cortisol, overnight dexamethasone suppression test, and sta ndard 2-day dexamethasone suppression test.

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Development of HAPE during time spent at 4559 m necessitated withdrawal from the study.

This committee, in light of this data, and any advice and evidence they wish to request, will if necessary report to the Trial Steering Committee (TSC) if there are any concerns regarding the activity or safety of the trial treatments.

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Because of the lack of information on dexamethasone use during breastfeeding, some experts recommend other corticosteroids be used instead, especially if a woman is nursing a newborn or preterm infant.

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Seven patients in the dexamethasone group and nine in the placebo group each met one exclusion criterion; one patient in the dexamethasone group met two exclusion criteria.

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The use of dexamethasone sodium phosphate injection in active tuberculosis should be restricted to those cases of fulminating or disseminated tuberculosis in which the corticosteroid is used for the management of the disease in conjunction with an appropriate antituberculous regimen.

Solutions of dexamethasone sodium phosphate injection are heat labile and must not be autoclaved.

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