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For a tumor with uncertain nature where the operative treatment extend is dependant on the benign or malignant nature of the tumor.

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Where indicated, Imatinib, Nilotinib, Dasatinib or DMSO as vehicle control were added to NK cells 30 min prior to the coculture and were present for the time of the assay.

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Thus, unclassifiable myelodysplastic syndromes (MDS-U) should not be diagnosed if a cytogenetic abnormality develops on TKI therapy in the absence of significant dysplasia or increased blasts.

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Imatinib (Gleevec) was the first drug to specifically target the BCR-ABL tyrosine kinase protein, and it quickly became the standard treatment for CML patients.

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Cases of fatal liver failure and severe liver injury requiring liver transplants have been reported with both short-term and long-term use of GLEEVEC.

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III studies investigating the benefit of omacetaxine in patients with CML post multiple TKI failure, with a significant proportion of these patients with baseline mutations, are ongoing.

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More sensitive blood tests, such as PCR and rarely FISH (see ), are usually done every three months on a blood sample after a person has a cytogenetic response in the bone marrow cells.

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Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION).

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Laparoscopic sphincter-preserving surgery (intersphincteric resection) after neoadjuvant imatinib treatment for gastrointestinal stromal tumor (GIST) of the rectum.

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